October home sales hit 3-year high; prices up 17% year over year

Consumer columnist David Lazarus talks with real estate reporter Alejandro Lazo, DataQuick analyst Andrew LePage and Bill McBride of the Calculated Risk blog about the strong October real estate numbers.

Southern California's real estate market bucked the typical fall slowdown last month, with buyers snapping up pricier homes and sales roaring up 18% over the prior month.

Sales hit a three-year high for an October, rising 25% from the same month last year. The median sale price for a Southland house last month was $315,000, equal to September and up 17% from October 2011, according to real estate research firm DataQuick.

A decline in the number of foreclosed homes has caused a shortage of inventory in entry-level neighborhoods, pushing up home prices. Demand from investors also remains strong, with these buyers snapping up a near-record level of homes last month.

"There is a growing appreciation of the fact that we've come to a sort of a point of inflection in the housing market," Stuart Gabriel, director of UCLA's Ziman Center for Real Estate, said. "The housing market, for a large number of factors, is perceived as having turned a corner."

The region's median hit bottom at $247,000 in April 2009 and has slowly crawled its way up since. The median is the point at which half the homes in the area sold for more and half for less.

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The rebound stems from more people chasing fewer homes. Interest rates remain near record-low levels, luring buyers. Investors with cash have poured into the market looking for cheap properties to flip or rent. And foreclosure resales have sunk to a five-year low, tightening the supply of cheap homes.

An estimated 21,075 newly built and previously owned houses and condominiums sold throughout the region last month. Coastal markets saw the biggest increases in sales — though every county posted double-digit gains compared with October last year. Orange County saw the biggest surge, with sales up 41%. Ventura rose 35%, San Diego, 31%, Los Angeles, 25%, San Bernardino, 18% and Riverside 13%.

Absentee buyers — investors and some second-home buyers — snapped up a near-record 28% of homes throughout the Southland last month. These investors paid a median $245,000, a 23% increase from October last year.

A recent report by real estate website Zillow showed that many investors and others are paying market value for foreclosed homes in the region, erasing the discount between foreclosed homes and regular properties. Discounts were marginal on bank-owned homes in September, with the discount in the Inland Empire just 2% and in the Los Angeles area 4% in September, Zillow said.

Bruce Norris, president of Norris Group, an investment company in Riverside that buys foreclosed homes, said he expects prices to increase in coming years as the Obama administration has encouraged banks to curtail foreclosures. That will push up prices, he said.

"It is policy driven," Norris said. "Since the policy is going to continue … you are about to see a pretty substantial price increase within the next two years."

Indeed, the high level of affordability ushered in by the housing crash could erode quickly in California. This week the California Assn. of Realtors reported that homes in the state are getting less affordable as property values rise. The group estimated that 49% of home buyers in the third quarter could afford a median-priced house in California, a decline from 51% last quarter. The rise in prices is offsetting the benefit to home shoppers from low mortgage interest rates.

Christopher Thornberg, a principal at Beacon Economics and one of the first to call attention to the housing bubble, said home shoppers should expect expensive housing in the Golden State for the foreseeable future. The reason: Construction of new homes remains highly expensive for builders.

"Why would it stop?" he said. "The economy is growing. Short of a fiscally led second recession, there is no reason in the world that it's going to do anything but to continue."

The region's lowest-cost areas — often those the most starved for inventory these days — posted the weakest sales numbers last month, according to DataQuick. The number of homes that sold below $200,000 in the region dropped 11% from October last year. Sales in these markets have slowed because of the drop in foreclosures, while increased demand has pushed up prices.

Sales of previously foreclosed-upon homes made up just 16% of the resale market last month, a drop from 17% last month and 33% in October 2011. Foreclosure resales peaked at 57% in February 2009.

In the meantime, sales surged in several mid- and higher-cost neighborhoods throughout Southern California in October, DataQuick said. Sales of homes between $300,000 and $800,000 increased 42% year over year. Sales of homes costing more than $500,000 were up 55% and sales of homes more than $800,000 rose 52%.

Bill McBride, lead writer for the housing blog Calculated Risk, said that with the upswing in prices homeowners are encouraged to keep their homes off the market.

"Why is there no inventory? I ask every real estate agent that, just to hear what they tell me. And they say people don't have enough equity in their homes and so they aren't listing them," McBride said. "That is a solid argument. But I also think the people are sensing that prices are going up and there is no urgency to sell."

alejandro.lazo@latimes.com

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Infinite Jukebox Lets You Listen to 'Call Me Maybe' Forever

By Philippa Warr, Wired UK

A Music Hack Day event in Boston has yielded The Infinite Jukebox — an app that creates infinitely long and ever-changing versions of uploaded tracks.

The Infinite Jukebox is the handiwork of Paul Lamere, director of developer platform for music intelligence company The Echo Nest and the man behind the Infinite Gangnam Style hack at Reykjavik’s Music Hack Day, and extends his previous project to its universal conclusion.

The app uses The Echo Nest analyzer — a music data service — to break the uploaded MP3 into individual beats. These beats can then be checked against one another to find similar-sounding points in the song. When the song is played, beat by beat there is a chance that the track will transition to one of the matched points rather than just playing normally.

Each track generates its own unique visualization that maps the beats around the circumference of a circle and shows possible transition paths between them.

“I was quite pleased at how the visualization turned out,” says Lamere. “I think it does a good job of helping the listener understand what is going on under the hood, and different songs have very different looks and color palettes. They can be quite attractive.”

The Infinite Jukebox works best with songs that have a lot of repetition, as they contain many transition opportunities — hence why we have been listening to “Call Me Maybe” by Carly Rae Jepson for 55 minutes but uploading an audio file of Richard Dreyfuss’ dramatic reading of the iTunes EULA yielded the error message, “Sorry, can’t make an infinite version of the song, it is too varied.”

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NBC names new top producer for ‘Today’

NEW YORK (AP) — NBC News is staying in-house in its effort to turn around the “Today” show.

The network on Wednesday appointed a 23-year veteran of the morning news show as its new executive producer. Don Nash began working for “Today” as a production assistant in NBC’s Burbank office in 1989 and will now run the four-hour broadcast.

Nash was most recently senior broadcast producer in the show’s control room. He replaces Jim Bell, who shifted to NBC Sports to run its Olympics broadcasts.

After nearly two decades of dominance, “Today” has slipped behind ABC’s “Good Morning America” in the ratings.

NBC also added another layer of management for the show, appointing Alexandra Wallace as the network’s executive in charge of the program.

Entertainment News Headlines – Yahoo! News

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Recurring Lyme Disease Symptoms Caused by New Infection, Study Finds

When people who have been treated for Lyme disease recover but later come down with its symptoms again, is the illness a relapse or a new infection?

The question has lingered for years. Now, a new study finds that repeat symptoms are from new infections, not from relapses.

The results challenge the notion, strongly held by some patients and advocacy groups, that Lyme disease, a bacterial infection, has a tendency to resist the usual antibiotic treatment and turn into a chronic illness that requires months or even years of antibiotic therapy.

The conclusion that new symptoms come from new infections is based on genetically fingerprinting the Lyme bacteria in people who have had the illness more than once, and finding that the fingerprints do not match. The result means that different episodes of Lyme in each patient were caused by different strains of the bacteria, and could not have been relapses.

The study, by researchers at the University of Pennsylvania and New York Medical College, in Valhalla, was published online on Wednesday in The New England Journal of Medicine.

An estimated 20,000 to 30,000 cases of Lyme disease occur each year in the United States. The disease is caused by a bacterium, Borrelia burgdorferi, that is carried by deer ticks. It often begins with an expanding zone of red skin — a symptom called erythema migrans — around the tick bite, but sometimes in other areas too. Fever, headaches, fatigue and aches and pains often follow.

Untreated, the disease can cause heart and neurological problems and arthritis, with symptoms that can come and go for years. Advanced cases that have gone months or years before being treated are most likely to result in persistent arthritis.

But when the disease is detected earlier, treatment with an antibiotic, usually two to four weeks of doxycycline, can get rid of the bacteria, according to infectious disease experts. Even advanced cases can be cleared by the drugs, doctors say, though an extra month or so of treatment may be needed. Symptoms like pain and fatigue can linger even after the bacteria are gone, possibly because the infection caused abnormalities in the immune system.

However, some doctors, patients and advocacy groups think that the bacteria themselves can somehow hang on despite treatment, even in cases caught early, and cause a chronic infection that requires long-term treatment with antibiotics. In some cases, people with unexplained pain, fatigue and cognitive problems have been told they had chronic Lyme disease even though blood tests found no evidence of the infection.

Several controlled studies have found that long-term antibiotics did not help people who had already been treated for Lyme disease but had such lingering problems.

Despite the data, the belief has hung on that Lyme disease bacteria can cause a chronic infection even after treatment.

The researchers who conducted the new study wanted to test that idea by finding out whether people who had repeated bouts of the disease were actually having relapses. They identified 17 patients who had erythema migrans — the rash — more than once between 1991 and 2011. Most had it twice, at least a year apart, but a few patients had it three times and one had four cases. Many had other symptoms as well, and more than half had signs of widespread systemic infection. All were treated, and recovered fully.

Lyme bacteria were grown from skin or blood samples taken from the patients when they had the rash, and the researchers analyzed a bacterial gene that varies from one strain to another. For each patient, they compared the genes from different cases of the rash. The genotypes did not match, which the researchers said proved that each rash represented a new infection, not a relapse.

In an editorial accompanying the article, Dr. Allen C. Steere, a Harvard professor who was the first to identify Lyme disease, said the new study supported previous research suggesting that new infections, not relapses, were the cause of new symptoms in people who had taken antibiotics to treat earlier cases of the disease.

Dr. Steere acknowledged that symptoms, sometimes disabling ones, do linger for months after treatment in as many as 10 percent of patients. Doctors do not know why. But, Dr. Steere said, “antibiotics are not the answer.”

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5-Hour Energy Is Cited in 13 Death Reports

Federal officials have received reports of 13 deaths over the last four years that cited the possible involvement of 5-Hour Energy, a highly caffeinated energy shot, according to Food and Drug Administration records and an interview with an agency official.

The disclosure of the reports is the second time in recent weeks that F.D.A. filings citing energy drinks and deaths have emerged. Last month, the agency acknowledged it had received five fatality filings mentioning another popular energy drink, Monster Energy.

Since 2009, 5-Hour Energy has been mentioned in some 90 filings with the F.D.A., including more than 30 that involved serious or life-threatening injuries like heart attacks, convulsions and, in one case, a spontaneous abortion, a summary of F.D.A. records reviewed by The New York Times showed.

The filing of an incident report with the F.D.A. does not mean that a product was responsible for a death or an injury or contributed in any way to it. Such reports can be fragmentary in nature and difficult to investigate.

The distributor of 5-Hour Energy, Living Essentials of Farmington Hills, Mich., did not respond to written questions about the filings, and its top executive declined to be interviewed. Living Essentials is a unit of the product’s producer, Innovation Ventures.

However, in a statement, Living Essentials said the product was safe when used as directed and that it was “unaware of any deaths proven to be caused by the consumption of 5-Hour Energy.”

Since the public disclosure of reports about Monster Energy, its producer, Monster Beverage of Corona, Calif., has repeatedly said that its products are safe, adding that they were not the cause of any of the health problems reported to the F.D.A.

Shares of Monster Beverage, which traded above $80 earlier this year, closed Wednesday at $44.74.

The fast-growing energy drink industry is facing increasing scrutiny over issues like labeling disclosures and possible health risks. Some lawmakers are calling on the F.D.A. to increase its regulation of the products and the New York State attorney general is investigating the practices of several producers.

Unlike Red Bull, Monster Energy and some other energy drinks that look like beverages, 5-Hour Energy is sold in a two-ounce bottle referred to as a shot. The company does not disclose the amount of caffeine in each bottle, but a recent article published by Consumer Reports placed that level at about 215 milligrams.

An eight-ounce cup of coffee, depending on how it is made, can contain from 100 to 150 milligrams of caffeine.

The F.D.A. has stated that it does not have sufficient scientific evidence to justify changing how it regulates caffeine or other ingredients in energy products. The issue of how to do so is complicated by the fact that some high-caffeine drinks, like Red Bull, are sold under agency rules governing beverages, while others, like 5-Hour Energy and Monster Energy, are marketed as dietary supplements. The categories have differing ingredient rules and reporting requirements.

In an interview Wednesday, Daniel Fabricant, the director of the agency’s division of dietary supplement programs, said the agency was looking into the death reports that cited 5-Hour Energy. He said that while medical information in such reports could rule out a link with the product, other reports could contain insufficient information to determine what role, if any, a supplement might have played.

Mr. Fabricant said that the 13 fatality reports that mentioned 5-Hour Energy had all been submitted to the F.D.A. by Living Essentials. Since late 2008, producers of dietary supplements are required to notify the F.D.A. when they become aware of a death or serious injury that may be related to their product.

Currently, the agency does not publicly disclose adverse event filings about dietary supplements like 5-Hour Energy. Companies that market energy drinks as beverages are not required to make such reports to the agency, although they can do so voluntarily, Mr. Fabricant said.

Along with caffeine, 5-Hour Energy contains other ingredients, like very high levels of certain B vitamins and an amino acid called taurine.

Reached by telephone, the chief executive of the Living Essentials, Manoj Bhargava, declined to discuss the filings and said he believed an article about the reports would cast the company in a negative light.

“I am not interested in making any comment,” Mr. Bhargava said.

Subsequently, the company issued a statement that said, among other things, that it took “reports of any potential adverse event tied to our products very seriously,” adding that the company complied “with all of our reporting requirements” to the F.D.A.

The company also stated that it marketed 5-Hour Energy to “hardworking adults who need an extra boost of energy.” The product’s label recommends that it not be used by woman who are pregnant or by children under 12 years of age.

The number of reports filed with the F.D.A. that mention 5-Hour Energy appears particularly striking. In 2010, for example, the F.D.A. received a total of 17 fatality reports that mentioned a dietary supplement or a weight loss product, two broad categories that cover more than 50,000 products, according to Mr. Fabricant, the F.D.A. official.

He added that it was difficult to put the volume of 5-Hour Energy filings into context because he believed that some supplement manufacturers were probably not following the mandated reporting rules and that consumers and doctors might also be unaware that they can file incident reports with the agency. Last year, the F.D.A. received only 2,000 reports about fatalities or serious injuries that cited dietary supplements and weight loss products, he said.

Another federal agency, the Substance Abuse and Mental Health Services Administration, reported late last year that more than 13,000 emergency room visits in 2009 were associated with energy drinks alone.

Along with Living Essentials, The Times sent queries last week to several producers asking whether they had received reports linking fatalities or serious injuries to their products.

Representatives for two of those companies — Red Bull and Coca-Cola, which sells NOS and Full Throttle — said they were unaware of any such reports. A representative for PepsiCo, which makes Amp, also said it was unaware of any such reports.

In addition to Red Bull, NOS, Full Throttle and Amp are also marketed as beverages, rather than as dietary supplements.

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Kupchak: If Phil Jackson hadn't hesitated he might be Lakers coach

History could have been different if Phil Jackson had said he was ready to coach the Lakers while meeting informally with two team executives on Saturday morning.

He might be the Lakers' coach right now, Lakers General Manager Mitch Kupchak said Tuesday.

"We would have gone back immediately and gone back and holed up with Dr. [Jerry] Buss and decided what we were going to do that day," Kupchak said.

Instead, Jackson asked Kupchak and team executive Jim Buss for two more days to think about a return after an 18-month layoff. The Lakers waited about 30 hours, didn't hear from him, and decided to hire Mike D'Antoni on Sunday night.

"There was no agreement to wait for [Jackson's] response on Monday," Kupchak said. "He told us that's when he would get back to us. I could see where he might interpret that as 'You guys would wait for me.' But I thought when I said I had to go on and interview other candidates that it was clear I had a job to do."

The Lakers interviewed D'Antoni by phone Saturday afternoon not long after meeting with Jackson at his Playa del Rey home. D'Antoni could not fly to Los Angeles last weekend because of recent knee-replacement surgery.

The Lakers hired D'Antoni mainly because of his high-flying offense. "He plays the way we see our team playing and our personnel executing," Kupchak said.

Kupchak himself wasn't sold on meshing Jackson's share-the-ball triangle offense with the Lakers' present-day roster. "I know the triangle," he said. "Obviously I wasn't convinced."

The Lakers decided to hire D'Antoni at 6 p.m. Sunday, half an hour before they tipped off against Sacramento at Staples Center.

Negotiations took some time, and then an unexpected electronic gaffe delayed the process once the sides agreed to a three-year, $12-million contact with a team option for a fourth year.

D'Antoni's fax machine was not working properly and could not transmit his signed contract back to the Lakers, according to a team spokesman. Finally, by 11:30 p.m. Sunday, the Lakers officially had a new coach, hiring D'Antoni despite the "We Want Phil!" chants by Lakers fans at Staples Center.

Kupchak acknowledged the "groundswell of support" for Jackson, who had the popular vote from the fans and received positive reviews from Kobe Bryant, Steve Nash and Dwight Howard, though Bryant and Nash also endorsed D'Antoni.

"There was a lot of pressure to seriously consider bringing Phil back," Kupchak said. "We sorted through the PR backlash and decided that we ultimately could withstand it."

They still had to withstand one other thing. They had to call Jackson on Sunday near midnight. He was sleeping.

"In those kind of situations, there's not a lot of small talk," Kupchak said. "He was very complimentary of Mike under the circumstances. I just told him . . . that we just felt the present makeup of the team and the kind of basketball we wanted to play going forward, we just felt that Mike D'Antoni was the choice.

"I didn't look forward to calling somebody at midnight to tell him that he's not going to get a job that he might or might not accept," Kupchak said. "But the only other thing I could do was wait until Monday morning and that would have been worse."

Jackson told The Times on Monday that the midnight phone call seemed "slimy."

"I wish it would have been a little bit cleaner," he said. "It would have been much more circumspect and respectful of everybody that's involved. It seemed slimy to be awoken with this kind of news. It's just weird."

Kupchak confirmed what was already stated by Jackson to The Times — salary wasn't discussed in their Saturday morning meeting. Neither was the concept of Jackson missing games on the road.

Jackson told Jim Buss and Kupchak he wanted the same communication between them on personnel decisions that he held in his second tenure with the team from 2005-11.

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Tesla's Big Win Proves EVs Are Ready for Primetime

Electric vehicles have hit the tipping point of mainstream acceptance, and you naysayers just lost your last reason for hating the technology.

MotorTrend magazine’s unanimous decision to name the Tesla Model S its car of the year is more than a big moment for Tesla Motors. It’s a big moment for electric vehicles and, more importantly, internal combustion. The award follows similar nods from Automobile and Yahoo. (Yes, Yahoo does cars.) That only underscores just how good the Model S is, and how solid its underlying technology is.

When an all-electric sedan from an upstart Silicon Valley firm can convince dyed-in-the-wool gearheads to unreservedly declare it the best car on the planet, a paradigm has shifted. No one’s saying we’ll all be driving cars with cords tomorrow, but this is the first big fissure in the internal combustion wall. One by one, the criticisms — electric cars are glorified golf cars, they lack adequate range, they’ll never be as practical as whatever — have been proven wrong.

“We’re going to look back and see this as a point at which the gears of history really turned,” company CEO Elon Musk said at the awards presentation Monday.

He’s right.

It’s worth noting the praise didn’t come from big ad spending, lush journo junkets to exotic locales or the typical wining and dining perpetrated by the major automakers. In other words, Tesla didn’t buy this award. The Model S won on merit alone, and that’s significant.

Look over the judging criteria behind these awards. They favor innovation and functionality. They’re focused on performance and practicality. And they put a premium on day-to-day livability as much as fit, finish and sex appeal. The Model S won on all those fronts, and that marks a shift in both the nature of the awards and the larger view of electric vehicles.

“If the Model S had a gas engine it still would have won,” Jonny Lieberman, MotorTrend Senior Editor and COTY judge told Wired. “It was, without question, the best car in this year’s competition.”

And competition was fierce.

The spate of awards came at a high point for auto enthusiasts. There’s a new Porsche 911 – the benchmark for attainable supercars – and Boxster (a personal favorite), the new Scion FR-S/Subaru BRZ (a clear appeal to gearheads that want a simple, fun and inexpensive sports car). The all-new BMW 3 Series was also in the running, as was Cadillac’s surprisingly fantastic ATS.

The Model S beat them all, with an unprecedented unanimous vote by the judges at MotorTrend.

We’ve been praising the virtues of electric vehicles for years. But the Model S is the departure from dinky, uninspiring econoboxes we’ve been forced to endure. It’s drop-dead gorgeous (if a bit safe). It’s an easy fit for five. It’s got more cargo capacity than most minivans. And those are just the high points on the functionality front.

Loads of pavement-rippling torque available at any speed matched with smooth delivery and Rolls-Royce levels of isolation are just part of the fun. EVs don’t have to worry about fitting a massive engine, bulging transmission and all the assorted ancillary components to make it go. The chassis is essentially a skateboard, with a battery mounted in the middle, allowing unlimited body and interior configurations that were completely unheard of just 10 years ago. The Model S’ platform is set to underpin the Model X SUV, further bolstering both Tesla’s flexibility and economies of scale, and the next few models in the automaker’s pipeline will use the lessons learned from the Model S to further hone the execution of a full line of EVs that will appeal to every price point and performance metric. Musk is even talking about a pickup truck.

And as for the big question – range – the Model S delivered in spades.

“The Models S is the cure for range anxiety,” Lieberman said. It can be driven normally, be it commuting to work or bombing a twisty mountain road, and with an EPA-rated range of 265 miles (MT managed a best run of 285 miles), it’s more than enough for the average driver. “Be honest with yourself and think about how many days per year you actually drive more than 200 miles,” Lieberman goes on. “Very, very few.”

Yes, we’re still in the early days, both for the S and its groundbreaking technology. Like any all-new car, it’s long-term reliability remains in question, especially since Tesla is new to the game.

“[The Model S is a] huge accomplishment from a brand new company in the big picture of the industry,” says Chelsea Sexton of the Lightning Rod Foundation. “It’s also an expensive car and an infant program, so it will undoubtedly have early technical issues and things that wouldn’t necessarily apply to other contenders – which makes the ‘engineering excellence’ and ‘value’ categories somewhat debatable.”

But for now, the Model S sits atop the heap, an innovative outlier that pleases on every level, and vindicates what we’ve been saying all along: EVs are the future and the future is now.

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Twilight cast bids farewell at final premiere

LOS ANGELES (Reuters) – Thousands of screaming fans lined the black carpet late on Monday for the final “Twilight” film premiere as the cast of “Breaking Dawn – Part 2″ bid farewell to the franchise and its loyal followers.

Robert Pattinson, Kristen Stewart, Taylor Lautner and other cast members greeted fans known as “Twi-hards,” many of whom had camped out for days in downtown Los Angeles to catch a glimpse of their favorite actors and see the film before it is released in theaters on Friday.

Breaking Dawn – Part 2 will see the love story of human Bella Swan (Stewart), vampire Edward Cullen (Pattinson) and werewolf Jacob Black (Lautner) come to a tantalizing end, when Bella and Edward are forced to protect their child from an ancient vampire coven.

Stewart, who was finally able to embrace her wild side by playing Bella as a vampire, hoped people would enjoy the ultimate transformation of her character in the film.

“Bella has worked pretty hard to get to the point where they can have it all, and it’s fun to be there. She’s always been human, but now that she’s not, you’re just in full blown vampire land and it feels funny in a great way,” Stewart told Reuters.

More than 2,200 fans from all over the world came to camp out on a concrete plaza in downtown Los Angeles last week, where Twilight movie studio Summit laid out activities and marathon screenings of the previous movies.

All of the film’s main actors spent time signing autographs and posing for photographs with the loyal fans who had camped out in chilly November weather over five days.

Pattinson, who plays vampire Edward Cullen, said he hoped the fans would like the franchise’s swan song.

“I hope they feel it kind of respects them, because I think in a lot of ways that’s what we were thinking when we were making it,” the actor said.

Lautner, who plays werewolf Jacob, said he’d be sad to say goodbye to the films and his character and hoped fans would be happy with the conclusion of the final film.

“I’m feeling fantastic, sad, emotional, there’s a lot of things going on inside of me right now but I’m just trying to soak up every moment because this means the world to me,” Lautner said.

The three lead stars were joined by fellow cast members including Nikki Reed, Ashley Greene, Kellan Lutz, Jackson Rathbone, Michael Sheen and Dakota Fanning, as well as director Bill Condon and author Stephenie Meyer, whose Twilight novels kicked off the franchise and phenomenon.

Meyer said she would miss watching the three lead cast members evolve as actors and characters in the films.

“It’s really been great to watch them grow up, particularly Kristen because her character gets to evolve so much in this film, and to watch her be all powerful and really get to where the character was always meant to go, to be the fiercest of the fierce, was really rewarding for me,” the author said.

(Reporting By Piya Sinha-Roy, editing by Paul Casciato)

Movies News Headlines – Yahoo! News

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Kidney Donors Given Mandatory Safeguards

ST. LOUIS — Addressing long-held concerns about whether organ donors have adequate protections, the country’s transplant regulators acted late Monday to require that hospitals thoroughly inform living kidney donors of the risks they face, fully evaluate their medical and psychological suitability, and then track their health for two years after donation.

Enactment of the policies by the United Network for Organ Sharing, which manages the transplant system under a federal contract, followed six years of halting development and debate.

Meeting at a St. Louis hotel, the group’s board voted to establish uniform minimum standards for a field long regarded as a medical and ethical Wild West. The organ network, whose initial purpose was to oversee donation from people who had just died, has struggled at times to keep pace with rapid developments in donations from the living.

“There is no question that this is a major development in living donor protection,” said Dr. Christie P. Thomas, a nephrologist at the University of Iowa and the chairman of the network’s living donor committee.

Yet some donor advocates complained that the measures did not go far enough, and argued that the organ network, in its mission to encourage transplants, has a conflict of interest when it comes to safeguarding donors.

Three years ago, the network issued some of the same policies as voluntary guidelines, only to have the Department of Health and Human Services insist they be made mandatory.

Although long-term data on the subject is scarce, few living kidney donors are thought to suffer lasting physical or psychological effects. Kidney donations, known as nephrectomies, are typically done laparoscopically these days through a series of small incisions. The typical patient may spend only a few nights in a hospital and feel largely recovered after several months.

Kidneys are by far the most transplanted organs, and there have been nearly as many living donors as deceased ones over the last decade. What data is available suggests that those with one kidney typically live as long as those with two, and that the risk of a donor dying during the procedure is roughly 3 in 10,000.

But kidney transplants, like all surgery, can sometimes end in catastrophe.

In May at Montefiore Medical Center in the Bronx, a 41-year-old mother of three died when her aorta was accidentally cut during surgery to donate a kidney to her brother. In other recent isolated cases, patients have received donor kidneys infected with undetected H.I.V. or hepatitis C.

Less clear are any longer-term effects on donors. Research conducted by the United Network for Organ Sharing shows that of roughly 70,000 people who donated kidneys between late 1999 and early 2011, 27 died within two years of medical causes that may — or may not — have been related to donation. For a small number of donors, their remaining kidney failed, and they required dialysis or a transplant.

The number of living donors — 5,770 in 2011 — has dropped 10 percent over the last two years, possibly because the struggling economy has made it difficult for prospective donors to take time off from work to recuperate. With the national kidney waiting list now stretching past 94,000 people, and thousands on the list dying each year, transplant officials have said they must improve confidence in the system so more people will donate.

The average age of donors has been rising, posing additional medical risks. And new ethical questions have been raised by the emergence of paired kidney exchanges and transplant chains started by good Samaritans who give an organ to a stranger.

Brad Kornfeld, who donated a kidney to his father in 2004, told the board that it had been impossible to find good information about what to expect, leaving him to search for answers on unreliable Internet chat rooms. He said he had almost backed out.

“If information is power,” said Mr. Kornfeld, a Coloradan who serves on the living donor committee, “the lack of information is crippling.”

Under the policies approved this week, the organ network will require hospitals to collect medical data, including laboratory test results, on most living donors to study lasting effects. Results must be reported at six months, one year and two years.

Similar regulations have been in place since 2000, but they did not require blood and urine testing, and hospitals were allowed to report donors who could not be found as simply lost.

That happened often. In recent years, hospitals have submitted basic clinical information — like whether donors were alive or dead — for only 65 percent of donors and lab data for fewer than 40 percent, according to the organ network. Although the network holds the authority, no hospital has ever been seriously sanctioned for noncompliance.

“It’s time we put some teeth into our policy,” said Jill McMaster, a board member from Tennessee.

By 2015, transplant programs will have to report thorough clinical information on at least 80 percent of donors and lab results on at least 70 percent. The requirements phase in at lower levels for the next two years.

Dr. Stuart M. Flechner of the Cleveland Clinic, the chairman of a coalition of medical societies that made recommendations to the organ network, said 9 of 10 hospitals would currently not meet the new requirement.

Donna Luebke, a kidney donor from Ohio who once served on the organ network’s board, said the new standards would matter only if enforcement were more rigorous. She noted that the organization was dominated by transplant doctors: “UNOS is nothing but the foxes watching the henhouse,” she said.

Another of the new regulations prescribes in detail the medical and psychological screenings that hospitals must conduct for potential donors. It requires automatic exclusion if the potential donor has diabetes, uncontrolled hypertension or H.I.V., among other conditions.

The new policies also require that hospitals appoint an independent advocate to counsel and represent donors, and that donors receive detailed information in advance about medical, psychological and financial risks.

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Alternative Fuels’ Long-Delayed Promise Might Be Near Fruition

WASHINGTON — For years, scientists and engineers have been juggling various combinations of acids, steam, bacteria, catalysts and the digestive juices of microorganisms to convert agricultural waste and even household garbage into motor fuel.

So far, such alternative fuels have not moved beyond small pilot plants, despite federal incentives to encourage companies to develop them.

But that could be about to change.

Officials at two companies that have built multimillion-dollar factories say they are very close to beginning large-scale, commercial production of these so-called cellulosic biofuels, and others are predicting success in the months to come.

In Columbus, Miss., KiOR has spent more than $200 million on a plant that is supposed to mix shredded wood waste with a patented catalyst, powdered to talcumlike consistency. Its process does in a few seconds what takes nature millions of years: removes the oxygen from the biomass and converts the other main ingredients, hydrogen and carbon, into molecules that can then be processed into gasoline and diesel fuel.

KiOR aims to turn out 13 million gallons of fuel a year and has already lined up three companies to buy its output, including FedEx and a joint venture of Weyerhauser and Chevron. KiOR said on Thursday that it had begun producing what it called “renewable crude” and intended to refine that into gasoline and diesel that it would begin shipping by the end of the month.

And Ineos, a European oil and chemical company, is putting the final touches on a plant in Vero Beach, Fla., that would cook wood and woody garbage until they broke down into tiny molecules of hydrogen and carbon monoxide. Those molecules would be pumped into a giant steel tank, where bacteria would eat them and excrete ethanol. The company has spent $130 million on the plant, which is supposed to make eight million gallons a year, about 1 percent of Florida’s ethanol demand. The plant is next to a county landfill, and executives covet the incoming garbage.

Both plants are far smaller than typical oil refineries, but commercial production at either one — or at any of several of the plants that are a step behind them — would be a major milestone in renewable energy.

At such plants, the goal is sometimes to make ethanol and sometimes gasoline or diesel fuel or their ingredients. The pathways to make the biofuels are varied. But the feedstocks have something in common: they are derived from plants and trees, but not from food crops like corn kernels, which are the basis of most of the biofuel currently made in the United States.

Often, the raw ingredients for the cellulosic biofuels are the wastes of farms, paper mills or households, with a value that is low or even negative, meaning people will pay the fuel producers to dispose of them. And the companies developing the new fuels say that their products produce far fewer carbon emissions than petroleum-based gasoline and diesel.

KiOR says that its fuel will release one-sixth the amount of carbon dioxide as an equivalent amount of petroleum fuel. That is mostly because every tree or woody plant fed into its process will eventually be replaced by a new tree or plant, which will suck carbon dioxide out of the atmosphere. And a byproduct of its factory is surplus electricity, which will be exported to the grid, displacing electricity that would otherwise be generated from natural gas or coal.

Ineos goes a step further, saying its production process actually reduces the overall amount of carbon in the atmosphere. “We could make the argument that we’re carbon-negative,” said Peter Williams, the chief executive. The reason, he said, is that electricity produced from its plant averts emissions that would have come from other electricity sources.

Just becoming the first company to produce commercial volumes of these alternative biofuels is no guarantee of commercial success. That depends on further optimizing production processes to get more gallons of fuel per ton of raw materials at lower operating costs.

Industry officials say that profits also depend on continued high prices for oil, the commodity that biofuels would replace, and a continuation of a federal government mandate that requires fuel blenders to mix a certain percentage of biofuels into the gasoline sold at service stations.

“Sustainability requires good economics,” Mr. Williams said.

Many companies have produced biofuel successfully, but only in quantities characteristic of a factory that makes fine whisky or perhaps perfume. The trick is to get reliability up and costs down to a level that allows operation on a large scale.

Government policy has anticipated far more technical progress than the industry has made. Congress set a goal of 250 million gallons of cellulosic biofuel for 2011 and 500 million gallons for this year, but the Environmental Protection Agency cut the requirement to six million gallons for 2012 because of the lack of commercial production.

Six governors, oil refiners and companies hurt by high corn prices have asked the agency to waive its requirements for ethanol and other renewable fuels. Some single out the corn ethanol mandate, but others want the quota for cellulosic fuels waived, too, partly because there is no actual production.

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